Neurodermatitis on the hands: causes, symptoms, and treatment options


Neurodermatitis, also known as lichen simplex chronicus, is a chronic skin condition that primarily affects the hands. It is characterized by intense itching, which leads to scratching and rubbing of the affected area. Over time, this repetitive behavior can cause thickened, leathery patches of skin to develop. In this article, we will explore the causes, symptoms, and treatment options for neurodermatitis on the hands.


The exact cause of neurodermatitis is unknown. However, it is believed to be a combination of genetic, environmental, and psychological factors. People with a family history of atopic dermatitis or other allergic conditions are more likely to develop neurodermatitis. Certain triggers, such as stress, anxiety, and irritants like harsh soaps or detergents, can also exacerbate the condition.


The primary symptom of neurodermatitis is intense itching, which can be debilitating and interfere with daily activities. The itching sensation is often described as a “burning” or “tingling” feeling. Scratching and rubbing the affected area provides temporary relief but can lead to a vicious cycle of more itching and scratching. Over time, the skin becomes thickened, rough, and leathery. In severe cases, the skin may crack, bleed, or develop open sores.

Treatment Options

1. Moisturizers: Keeping the skin well-hydrated is essential in managing neurodermatitis. Regularly applying moisturizers can help soothe the skin and reduce itching. Look for fragrance-free and hypoallergenic options to minimize the risk of irritation. 2. Topical corticosteroids: These medications are commonly prescribed to reduce inflammation and itching. They come in various strengths, and your doctor will determine the appropriate potency based on the severity of your symptoms. It is important to follow the prescribed dosage and duration to avoid potential side effects. 3. Antihistamines: Oral antihistamines can help relieve itching and promote better sleep. They work by blocking the effects of histamine, a chemical released during an allergic reaction. However, some antihistamines can cause drowsiness, so it is advisable to take them before bedtime. 4. Avoid triggers: Identifying and avoiding triggers that worsen your symptoms is crucial in managing neurodermatitis. Common triggers include stress, certain fabrics, harsh soaps or detergents, and extreme temperatures. Keeping a diary to track your symptoms and potential triggers can be helpful in identifying patterns. 5. Stress management: Stress can exacerbate neurodermatitis symptoms. Finding healthy ways to manage stress, such as practicing relaxation techniques, engaging in regular exercise, or seeking therapy, can help reduce flare-ups. 6. Phototherapy: In some cases, light therapy may be recommended to treat neurodermatitis. This involves exposing the affected skin to controlled amounts of ultraviolet (UV) light. Phototherapy can help reduce inflammation and itching, but it should be done under medical supervision to minimize the risk of side effects. 7. Immunosuppressants: In severe cases of neurodermatitis that do not respond to other treatments, immunosuppressant medications may be prescribed. These medications work by suppressing the immune system’s response, reducing inflammation and itching. However, they carry potential risks and side effects, so they are typically reserved for severe cases.


Neurodermatitis on the hands can be a challenging condition to manage, but with the right treatment approach, symptoms can be controlled. It is important to work closely with a healthcare professional to develop a personalized treatment plan that addresses your specific needs. By following a comprehensive treatment plan and making lifestyle adjustments, individuals with neurodermatitis can experience relief from itching and improve their overall quality of life.